Flow synthesis of a key intermediate of Bortezomib anti-cancer drug

Check out our last contribution in flow chemistry dealing with the flow synthesis of an a-amino boronic ester as key intermediate of Bortezomib anti-cancer drug published in React. Chem. & Eng. 2022 DOI: 10.1039/D2RE00099G. Congratulations to Titouan Desrues and the API team (Maria Ivanova, Thibaud Bregent and Laly Donnier-Valentin) from UMR 6014 COBRA. This work is part of the API program supported by the European Union through the operational program FEDER/FSE 2014-2020 (n°20E04976) and FNADT-DRACCARE program 2020-2023 ((N)15179). This work has been partially supported by Université Rouen Normandie, INSA Rouen Normandie, Centre National de la Recherche Scientifique (CNRS), European Regional Development Fund (ERDF), Labex SynOrg (ANR-11-LABX-0029), Carnot Institute I2C, the graduate school for research XL-Chem (ANR-18-EURE-0020 XL CHEM) and by Région Normandie.